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Natural origin
Nicotine derived from natural tobacco
Extracted from graded tobacco leaf and stem, refined to 99.9% and traceable back to the incoming lot. The route buyers choose when natural origin has to be documented.
- OriginNatural tobacco
- Assay99.9% min
- Isomer(S)-nicotine
- TraceabilityTo leaf lot
Why origin matters
Natural origin you can evidence on paper
For many markets and many customers, where the nicotine came from is not a marketing line. It is a question on a registration dossier, a customs declaration or a customer audit, and it has to be answered with records rather than assurances.
Tobacco derived nicotine from our plant carries that record. Incoming leaf is graded and lot numbered, and every downstream stage references that lot, so a finished drum can be walked back to the tobacco it started as.
Naturally occurring isomer
Nicotine extracted from tobacco is the (S)-isomer, the form that occurs in the plant. This is the practical difference buyers ask about most often when comparing tobacco derived material with synthetic material, and it is worth confirming which your market and your monograph expect before you commit.
The five stage route
Powdering, pretreatment, extraction, multi-stage purification and release. Our extraction process page sets out each stage with the machinery used.
Purity and specification
Released specification
Tobacco derived material is released against the same limits as our flagship grade, with the alkaloid profile reported on every certificate.
| Parameter | Method | Specification |
|---|---|---|
| Assay, nicotine | GC | 99.9% min |
| Origin | Declaration | Extracted from natural tobacco, lot traceable |
| Appearance | Visual | Clear, colourless to pale yellow oily liquid |
| Isomer | Polarimetry / chiral GC | (S)-nicotine, levorotatory |
| Nornicotine, anabasine, anatabine | GC / HPLC | Within monograph limit |
| Water content | Karl Fischer | Within monograph limit |
| Heavy metals | ICP-MS | Within ICH Q3D limits |
| Pesticide residues | GC-MS / LC-MS | Tested, report available on request |
| Residual solvents | GC headspace | Within ICH Q3C limits |
Packaging, storage and documents
How it is packed, stored and documented
Packaging
- Amber glass bottles100 g, 500 g and 1 kg, induction sealed
- HDPE / fluorinated drums5 kg, 10 kg and 25 kg
- Stainless steel drums50 kg and 200 kg for bulk offtake
- Inert headspaceNitrogen blanketed and sealed at filling
- LabellingBatch number, manufacturing and retest date, UN hazard labels
- Export packingUN certified outer packing with dangerous goods declaration
Storage and shelf life
- TemperatureCool, dry store, away from direct sunlight and heat
- LightKeep in original light protected packing
- AtmosphereReseal under nitrogen after sampling to limit oxidation
- SegregationStore away from oxidising agents, acids and foodstuffs
- AccessLocked, access controlled store as required by local law
- Retest period24 months from manufacture in unopened original packing
Documentation with every batch
- Certificate of analysisBatch specific, issued with every despatch
- Material safety data sheetGHS format, 16 section MSDS
- Specification sheetParameters, methods and release limits
- DeclarationsNon GMO, allergen, TSE/BSE and residual solvent statements
- Shipping documentsPacking list, invoice, COO and DG declaration
- On requestStability summary, method of analysis, regulatory support documents
Ordering
Minimum order, samples and lead time
Qualification samples first, then scheduled commercial volumes. Supply is against verified end use, licence and import permit.
Send your requirement
Grade, quantity, destination market and intended application, with your company details.
Compliance check
We verify licence, import permit and end use, then share the specification sheet, MSDS and a recent CoA.
Sample despatch
A qualification sample is packed and shipped under dangerous goods rules with full paperwork.
Qualification and order
You test against your own method, we confirm price, batch size and despatch schedule.
Buyer questions
Frequently asked
What is the difference between tobacco derived and synthetic nicotine?
Tobacco derived nicotine is extracted from the plant and is the naturally occurring (S)-isomer. Synthetic nicotine is manufactured without tobacco. The two are treated differently by some regulators, so the right choice depends on your market and your registration.
Can you document the natural origin for our dossier?
Yes. We issue an origin declaration alongside the batch CoA, and the batch record traces the material back to the graded tobacco lot it was extracted from.
Is a pesticide residue report available?
Yes, on request. Tell us which residue panel your market requires and we will confirm what we can test and report against before despatch.
What is the minimum order quantity?
Commercial supply starts at 1 kg, with 100 g samples for qualification. Contract volumes are quoted separately.
Derived from nature, delivered to the world
Request an origin declaration and current CoA
Tell us your destination market and application, and we will confirm documentation, lead time and pricing.
Request COA & price Email info@mccoynic.com Contact us
Business to business supply only. Nicotine is a regulated substance and is toxic in concentrated form. We supply licensed manufacturers, formulators and research institutions against verified end use, valid import permits and applicable local law. We do not sell to individuals or for consumer use, and we do not provide production methods.